SNX 5422

Drug Profile

SNX 5422

Alternative Names: 113; PF-04929113; PF-113; PF-4929113; SNX-5422

Latest Information Update: 31 Jul 2017

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At a glance

  • Originator Serenex
  • Developer Esanex; Serenex
  • Class Amides; Antineoplastics; Indazoles; Small molecules
  • Mechanism of Action HSP90 heat-shock protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cancer
  • Phase I Chronic lymphocytic leukaemia; Haematological malignancies; Neuroendocrine tumours; Solid tumours
  • No development reported Lung cancer; Non-Hodgkin's lymphoma

Most Recent Events

  • 01 Jul 2017 Esanex completes a phase I trial for Solid tumours (Combination therapy) in USA (NCT01892046)
  • 06 Jun 2017 Safety and efficacy data from a phase I trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 06 Jun 2017 Esanex completes enrolment in a phase I trial for Solid tumours in USA prior to June 2017
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