Rolapitant

Drug Profile

Rolapitant

Alternative Names: Rolapitant hydrochloride; SCH-619734; VARUBI; Varuby

Latest Information Update: 16 Oct 2017

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At a glance

  • Originator Schering-Plough
  • Developer Merck & Co; Schering-Plough; TESARO
  • Class Antiemetics; Ethers; Piperidines; Pyrrolidines; Small molecules; Spiro compounds
  • Mechanism of Action Neurokinin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Chemotherapy-induced nausea and vomiting
  • Discontinued Cough; Postoperative nausea and vomiting

Most Recent Events

  • 09 Oct 2017 Tesaro in collaboration with Duke University initiates a phase II trial for Chemotherapy induced nausea and vomiting (Combination therapy, Prevention) (NCT02991456)
  • 08 Aug 2017 Launched for Chemotherapy induced nausea and vomiting (Combination therapy, Prevention) in Austria, Finland, United Kingdom and Denmark (PO)
  • 03 Jun 2017 Launched for Chemotherapy induced nausea and vomiting (Combination therapy, Prevention) in Germany (PO)
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