BHQ 880

Drug Profile

BHQ 880

Alternative Names: Anti-DKK1 mAb; Anti-DKKK-1 neutralising antibody (BHQ880); BHQ-880

Latest Information Update: 20 Aug 2015

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At a glance

  • Originator MorphoSys; Novartis
  • Class Antibodies; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action DKK1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple myeloma
  • Phase I Solid tumours

Most Recent Events

  • 20 Aug 2015 BHQ 880 is still in phase-II development for Multiple myeloma in USA and Europe
  • 01 Nov 2013 Novartis completes a phase II trial in Multiple myeloma (treatment naive, monotherapy) in USA, Germany and France (IV) (NCT01302886)
  • 01 May 2013 Novartis completes a phase II trial in Multiple myeloma (treatment naive, combination therapy) in USA, Spain and United Kingdom (IV) (NCT01337752)
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