LGD 6972

Drug Profile

LGD 6972

Alternative Names: Compound G; Compound H; Cpd G; Cpd H; GCGR Antagonist Program - Ligand Pharmaceuticals; GRA; LGD-6972; LGD-6972 sodium salt; MB-11262

Latest Information Update: 10 Oct 2017

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At a glance

  • Originator Metabasis Therapeutics
  • Developer Ligand Pharmaceuticals
  • Class Antihyperglycaemics; Small molecules
  • Mechanism of Action Glucagon receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Type 2 diabetes mellitus
  • Preclinical Type 1 diabetes mellitus

Most Recent Events

  • 11 Sep 2017 Pharmacokinetics, adverse events and pharmacodynamics data from a phase I trial in Type 2 diabetes presented at 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD - 2017)
  • 05 Sep 2017 Pharmacodynamic data from preclinical studies in Type 2 diabetes released by Ligand Pharmaceuticals
  • 05 Sep 2017 Top-line efficacy and adverse events data from phase II trial in Type 2 diabetes released by Ligand Pharmaceuticals
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