Drug Profile


Alternative Names: BIIB 050; KNS-760704; RPPX

Latest Information Update: 16 Jan 2017

Price : $50

At a glance

  • Originator University of Virginia
  • Developer Biogen Idec; Knopp Biosciences; National Institute of Allergy and Infectious Diseases
  • Class Antiparkinsonians; Benzothiazoles; Neuroprotectants; Small molecules
  • Mechanism of Action Antioxidants; Apoptosis inhibitors; Dopamine receptor agonists; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Hypereosinophilic syndrome

Most Recent Events

  • 04 Jan 2017 Knopp Biosciences received patent protection entitled “Compositions and Methods for Treating Conditions Related to Increased Eosinophils” for dexpramipexole in USA
  • 03 Dec 2016 Efficacy and adverse events data from a phase II trial in Hypereosinophilic syndrome presented at the 58th Annual Meeting and Exposition of the American Society of Haematology
  • 03 Dec 2016 Knopp Biosciences completes enrolment in its phase II trial for Hypereosinophilic Syndrome in USA (PO) before December 2016
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