Drug Profile


Alternative Names: Anti-LINGO 1; Anti-LINGO-1 antibody; BIIB-033

Latest Information Update: 18 Oct 2017

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At a glance

  • Originator Biogen Idec; Dyax
  • Developer Biogen
  • Class Antibodies; Monoclonal antibodies; Neuropsychotherapeutics
  • Mechanism of Action Cell differentiation stimulants; LINGO-1-protein-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Optic neuritis

Most Recent Events

  • 26 Sep 2017 Phase-II clinical trials in Multiple sclerosis (Adjunctive treatment) in USA (IV) (NCT03222973)
  • 24 Aug 2017 Phase-II development for Multiple sclerosis is ongoing in Canada, Czech Republic, France, Hungary, Italy, Netherlands, Poland, Russia, Serbia, Spain, USA, United Kingdom (IV,infusion) (Biogen pipeline, August 2017)
  • 24 Jul 2017 Biogen plans a phase II trial for Multiple sclerosis (Adjunctive treatment) (NCT03222973)
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