Drug Profile


Alternative Names: CD-NP

Latest Information Update: 23 Feb 2017

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At a glance

  • Originator Mayo Clinic
  • Developer Capricor Therapeutics; Mayo Clinic
  • Class Cardiovascular therapies; Heart failure therapies; Natriuretic peptides
  • Mechanism of Action Atrial natriuretic factor receptor A agonists; Atrial natriuretic factor receptor B agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute heart failure; Chronic heart failure
  • Phase I Myocardial infarction

Most Recent Events

  • 04 Apr 2017 Mayo clinic plans a phase I trial for Acute heart failure in USA (NCT03091998)
  • 16 Feb 2017 Capricor Therapeutics has elected to terminate its license agreement with the Mayo Clinic for natriuretic peptide receptor agonists, including Cenderitide
  • 15 Dec 2016 Biomarkers information updated
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