Research programme: S-nitrosothiol modulating agents - Alpine Immune Therapeutics

Drug Profile

Research programme: S-nitrosothiol modulating agents - Alpine Immune Therapeutics

Alternative Names: GSNORi's - Alpine Immune Sciences; N 6547; N 91121; N 91138; N 91169; N6022 analogues; S nitrosoglutathione reductase inhibitors - Alpine Immune Sciences

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator NitroMed
  • Developer Alpine Immune Sciences
  • Class Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator modulators; Glutathione-independent formaldehyde dehydrogenase inhibitors; Nitric oxide stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Chronic obstructive pulmonary disease; Cystic fibrosis; Inflammatory bowel diseases; Respiratory tract disorders

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Chronic-obstructive-pulmonary-disease in USA (IV, Injection)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Chronic-obstructive-pulmonary-disease in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cystic-fibrosis in USA (IV)
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