Research programme: NADPH oxidase inhibitors - GenKyoTex

Drug Profile

Research programme: NADPH oxidase inhibitors - GenKyoTex

Alternative Names: GKT-03; GKT-136901; GKT-771; GKT-901; HTS programme; NOX inhibitors - GenKyoTex

Latest Information Update: 29 Nov 2017

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At a glance

  • Originator GenKyoTex
  • Class Analgesics; Anti-inflammatories; Antineoplastics; Small molecules
  • Mechanism of Action CYBB protein inhibitors; NADPH oxidase inhibitors; NOX1 protein inhibitors; NOX4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cardiovascular disorders; Inflammation; Pain
  • Research Cancer; Hearing loss; Parkinson's disease
  • Discontinued Diabetic nephropathies; Idiopathic pulmonary fibrosis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cardiovascular-disorders in Switzerland
  • 26 Oct 2017 Preclinical development in Cardiovascular disorders is ongoing
  • 26 Oct 2017 Early research in Parkinson's disease in France (unspecified route)
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