Research programme: CNS disease therapeutics - Bristol-Myers Squibb

Drug Profile

Research programme: CNS disease therapeutics - Bristol-Myers Squibb

Alternative Names: Disease activated CNS therapeutics; pH-activated CNS therapeutics

Latest Information Update: 06 Oct 2014

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At a glance

  • Originator NeurOp
  • Developer Bristol-Myers Squibb; NeurOp
  • Class Small molecules
  • Mechanism of Action NR2B N-Methyl D-Aspartate receptor modulators; NR2B N-Methyl-D-Aspartate antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cerebral ischaemia; Major depressive disorder; Pain

Most Recent Events

  • 02 Oct 2014 Preclinical development is ongoing in the US
  • 14 Dec 2011 Bristol-Myers Squibb extends collaboration with NeurOp for the development of NR2B NMDA receptor antagonists for the treatment of Depression and Neuropathic pain
  • 27 Jul 2011 NeurOp receives National Institutes of Health grant from the National Institute of Neurological Disorders and Stroke for preclinical development in Ischaemia
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