Drug Profile
INT 767
Alternative Names: Dual FXR/TGR5 agonists - Intercept Pharmaceuticals; FXR & TGR5 BA-derived backups - Intercept Pharmaceuticals; INT-767Latest Information Update: 10 Nov 2023
Price :
$50
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At a glance
- Originator Intercept Pharmaceuticals
- Class Anti-inflammatories; Antifibrotics; Bile acids and salts; Cholanes; Hepatoprotectants; Small molecules; Sulfates
- Mechanism of Action Farnesoid X-activated receptor agonists; G protein-coupled receptor agonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Diabetic nephropathies; Hepatic fibrosis; Metabolic disorders; Non-alcoholic steatohepatitis
Most Recent Events
- 08 Nov 2023 Intercept Pharmaceuticals has been acquired by Alfasigma
- 12 Nov 2021 Pharmacodynamics data from preclinical studies in Hepatic fibrosis presented at the 72nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2021)
- 11 Apr 2018 Pharmacodynamics data from a preclinical trial in Firbosis presented at the International Liver Congress 2018 (ILC-2018)