KX 01

Drug Profile

KX 01

Alternative Names: KX-01; KX-2391

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Kinex Pharmaceuticals
  • Developer Athenex; Hanmi Pharmaceutical; Kinex Pharmaceuticals; PharmaEssentia Corporation
  • Class Acetamides; Antineoplastics; Morpholines; Pyridines; Skin disorder therapies; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Caspase stimulants; Interleukin 2 inhibitors; Keratinocyte inhibitors; Proto-oncogene protein c-bcl-2 inhibitors; Src-Family kinase inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Actinic keratosis
  • Phase II Psoriasis
  • Phase I/II Solid tumours
  • Phase I Acute myeloid leukaemia
  • No development reported Prostate cancer

Most Recent Events

  • 25 Sep 2017 Athenex plans a second phase III AK004 trial for Actinic keratosis in USA (Topical) in September 2017 (NCT03285490)
  • 15 Sep 2017 Athenex initiates a phase III trial in Actinic keratosis in USA (NCT03285490)
  • 15 Sep 2017 Phase-III clinical trials in Actinic keratosis in USA (Topical)
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