Research programme: enzyme inhibitors - Lixte Biotechnology Holdings

Drug Profile

Research programme: enzyme inhibitors - Lixte Biotechnology Holdings

Alternative Names: Cancer therapeutics - Lixte; LB-1.2; LB-102; LB-2.1; LB-201; LB-205; LB-300 series - Lixte; LB-400 series - Lixte; Neurological therapeutics - Lixte

Latest Information Update: 30 Apr 2013

Price : $50

At a glance

  • Originator Lixte Biotechnology Holdings
  • Developer Lixte Biotechnology Holdings; National Institute of Neurological Disorders and Stroke; National Institutes of Health (USA)
  • Class
  • Mechanism of Action Histone deacetylase inhibitors; Phosphoprotein phosphatase inhibitors; Signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer; Gaucher's disease; Mycoses
  • Research Amyotrophic lateral sclerosis; Neurological disorders

Most Recent Events

  • 25 Apr 2013 Lixte Biotechnology Holdings initiates a phase I trial of its lead candidate, LB 100, in Solid tumours
  • 21 Dec 2011 Preclinical trials in Gaucher's disease in USA (unspecified route)
  • 01 Feb 2011 Preclinical development is ongoing in USA
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