Sirolimus albumin bound

Drug Profile

Sirolimus albumin bound

Alternative Names: ABI-009; Nab-rapamycin; Nab-sirolimus

Latest Information Update: 07 Dec 2017

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At a glance

  • Originator Abraxis BioScience
  • Developer AADi; Children's Oncology Group; National Cancer Institute (USA)
  • Class Anti-infectives; Antifungals; Antineoplastics; Lactones; Macrolides; Polyenes; Pyridines
  • Mechanism of Action MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Perivascular epithelioid cell tumours
  • Phase I/II Bladder cancer; Sarcoma
  • Phase I Pulmonary arterial hypertension; Solid tumours

Most Recent Events

  • 24 Aug 2017 Phase-I/II clinical trials in Sarcoma (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT03190174)
  • 24 Jul 2017 Phase-I clinical trials in Solid tumours (Combination therapy, Recurrent, Second-line therapy or greater, In infants, In children, In adolescents, In adults) in USA (IV) (NCT02975882)
  • 24 Jul 2017 Phase-I clinical trials in Solid tumours (In adolescents, In children, In infants, Recurrent, Second-line therapy or greater, In adults, Monotherapy) in USA (IV) (NCT02975882)
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