Drug Profile


Alternative Names: Liver-specific microRNA-122 antagonist - Roche; LNA-antimiR™-122; miR-122 antagonist - Roche; Miravirsen sodium; SPC-3649

Latest Information Update: 22 Sep 2015

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At a glance

  • Originator Santaris Pharma
  • Developer Roche
  • Class Antivirals; Oligonucleotides; RNA
  • Mechanism of Action MIRN122 microRNA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis C

Most Recent Events

  • 22 Sep 2015 Phase-II development for Hepatitis C (Treatment-naive) is ongoing in Germany, Netherlands, Poland, Puerto Rico, Slovakia and USA
  • 21 Sep 2015 Phase-II development for Hepatitis C (Treatment-experienced) is ongoing in USA and Puerto Rico (SC)
  • 01 Jun 2013 Santaris initiates enrolment in a phase II trial in Hepatitis C (treatment-experienced patients) in USA and Puerto Rico (NCT01872936)
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