BMS 986036

Drug Profile

BMS 986036

Alternative Names: ARX-618; BMS-986036; FGF-21 mimetic proteins - Ambrx/Merck; PEG-FGF21; Pegylated FGF21; Pegylated-fibroblast growth factor-21 - Ambrx/Bristol-Myers Squibb

Latest Information Update: 20 Oct 2017

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At a glance

  • Originator Ambrx
  • Developer Bristol-Myers Squibb
  • Class Fibroblast growth factors; Obesity therapies; Polyethylene glycols; Proteins
  • Mechanism of Action Fibroblast growth factor 21 agonists; Fibroblast growth factor replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Fibrosis; Non-alcoholic steatohepatitis; Type 2 diabetes mellitus

Most Recent Events

  • 22 Sep 2017 Bristol-Myers Squibb completes a phase I trial in Healthy volunteers in USA (NCT03198182)
  • 29 Jun 2017 Bristol-Myers Squibb plans a phase I trial in Healthy volunteers in USA (NCT03198182)
  • 28 Jun 2017 Bristol-Myers Squibb initiates enrolment in a phase I trial in Healthy volunteers in USA (NCT03198182)
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