Drug Profile


Alternative Names: 1014802; [14C]-BIIB 074; BIIB 074; CNV 1014802; GSK1014802; Vixotrigine

Latest Information Update: 01 Nov 2017

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At a glance

  • Originator GlaxoSmithKline
  • Developer Biogen; GlaxoSmithKline
  • Class Analgesics; Neuropsychotherapeutics; Pyrrolidines; Small molecules
  • Mechanism of Action Nav1.7-voltage-gated-sodium-channel-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Trigeminal neuralgia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Neuropathic pain; Trigeminal neuralgia

Highest Development Phases

  • Phase III Trigeminal neuralgia
  • Phase II Erythromelalgia; Neuropathic pain
  • Discontinued Bipolar disorders

Most Recent Events

  • 30 Oct 2017 Biogen initiates enrolment in a phase I drug interaction trial in healthy volunteers in USA (NCT03324685)
  • 06 Mar 2017 Phase-III clinical trials in Trigeminal neuralgia in Hungary (PO) (EudraCT2016-002473-35)
  • 14 Feb 2017 Phase-III clinical trials in Trigeminal neuralgia in Austria (PO) (EudraCT2016-001449-16)
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