Apabetalone

Drug Profile

Apabetalone

Alternative Names: RVX-000222; RVX-208

Latest Information Update: 04 Oct 2017

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At a glance

  • Originator Resverlogix Corporation
  • Class Anti-inflammatories; Cardiovascular therapies; Quinazolines; Small molecules
  • Mechanism of Action Bromodomain and extraterminal domain protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Acute coronary syndromes; Atherosclerosis; Low HDL cholesterol
  • Phase II Prediabetic-state
  • Phase I Alzheimer's disease
  • Preclinical Renal failure

Most Recent Events

  • 26 Aug 2017 Updated efficacy data from the phase II trial in Atherosclerosis presented at the Annual Congress of the European Society of Cardiology (Aug-2017)
  • 26 Aug 2017 Pooled pharmacodynamics data from phase II SUSTAIN and ASSURE trial in Atherosclerosis presented at the Annual Congress of the European Society of Cardiology (USC-Card-2017)
  • 28 Jun 2017 Phase-III clinical trials in Acute coronary syndromes in Taiwan, Russia (PO)
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