XL 888

Drug Profile

XL 888

Alternative Names: EXEL-4888; XL888

Latest Information Update: 25 Aug 2016

Price : $50

At a glance

  • Originator Exelixis
  • Developer Exelixis; H. Lee Moffitt Cancer Center and Research Institute
  • Class Antineoplastics; Small molecules
  • Mechanism of Action HSP90 heat-shock protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Malignant melanoma

Most Recent Events

  • 01 Aug 2016 Phase-I clinical trials in Malignant melanoma (Late-stage disease, Inoperable/Unresectable, Combination therapy) in USA (PO) (NCT02721459)
  • 29 Mar 2016 H. Lee Moffitt Cancer Center and Research Institute plans a phase I trial for Malignant melanoma (Combination therapy, Late-stage disease, Inoperable/Unresectable) in USA (NCT02721459)
  • 16 Nov 2014 Interim efficacy and adverse events data from a phase I trial in Malignant melanoma released by Exelixis
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