Drug Profile


Alternative Names: hTERT-Ad; OBP-301; Telomelysin

Latest Information Update: 17 Jul 2017

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At a glance

  • Originator Oncolys Biopharma
  • Developer Okayama University; Oncolys BioPharma
  • Class Antineoplastics; Oncolytic viruses; Viral proteins
  • Mechanism of Action Telomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Malignant melanoma
  • Phase I/II Head and neck cancer; Hepatocellular carcinoma; Non-small cell lung cancer; Oesophageal cancer
  • Preclinical Adenocarcinoma; Neuroblastoma
  • No development reported Breast cancer; Mesothelioma; Osteosarcoma; Skin cancer; Soft tissue sarcoma

Most Recent Events

  • 07 Jul 2017 Oncolys BioPharma enrols the first patient in a phase I trial for Oesophageal cancer in Japan
  • 29 Jun 2017 Oncolys BioPharma submits a clinical trial notification (CTN) with the Pharmaceuticals and Medical Devices Agency (PMDA) for Solid tumours in Japan
  • 27 Jun 2017 Oncolys initiates enrolment in a phase I trial for Oesophageal cancer in Japan
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