Drug Profile


Alternative Names: OBP-301; Telomelysin

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Oncolys Biopharma
  • Developer Okayama University; Oncolys BioPharma
  • Class Antineoplastics; Oncolytic viruses; Viral proteins
  • Mechanism of Action Telomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Malignant melanoma
  • Phase I/II Head and neck cancer; Hepatocellular carcinoma; Non-small cell lung cancer; Oesophageal cancer
  • Phase I Solid tumours
  • Preclinical Neuroblastoma
  • No development reported Adenocarcinoma; Breast cancer; Mesothelioma; Osteosarcoma; Skin cancer; Soft tissue sarcoma

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Adenocarcinoma in USA (Intratumoural, Injection)
  • 01 Oct 2017 Phase-I clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Japan (Intratumoural) (NCT03172819)
  • 07 Jul 2017 Oncolys BioPharma enrols the first patient in a phase I trial for Oesophageal cancer in Japan
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