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Peltopepimut-S

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Drug Profile

Peltopepimut-S

Alternative Names: HPV-16; HPV-SLP; HPV16-SLP; Human papilloma virus type 16 E6/E7 synthetic long peptides - ISA Pharmaceuticals; ISA 101b; ISA-101; ISA-HPV; ISA-HPV-01; ISA-HPV-SLP®; Peltopepimut S; SLP-HPV-01

Latest Information Update: 07 Jan 2025

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At a glance

  • Originator ISA Pharmaceuticals
  • Developer Bristol-Myers Squibb; ISA Pharmaceuticals; Regeneron Pharmaceuticals; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; Papillomavirus vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Vulvar intraepithelial neoplasia; Cervical cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cervical cancer; Head and neck cancer; Oropharyngeal cancer; Solid tumours; Squamous cell cancer; Vulvar intraepithelial neoplasia
  • Phase I/II Anal intraepithelial neoplasia

Most Recent Events

  • 13 Sep 2024 Efficacy data from a phase II trial in Squamous cell cancer presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 31 May 2024 Efficacy and adverse events data from a phase-II trial in cervical cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 31 May 2024 Adverse events and efficacy data from a phase II trial in Oropharyngeal cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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