RG 4929

Drug Profile

RG 4929

Alternative Names: 11 Beta HSD inhibitor; R4929; RG4929; RO 5093151

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche
  • Class Antihyperglycaemics; Small molecules
  • Mechanism of Action 11-beta hydroxysteroid dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Glaucoma; Ocular hypertension
  • Discontinued Non-alcoholic fatty liver disease; Type 2 diabetes mellitus

Most Recent Events

  • 31 Jul 2016 Roche completes a phase I trial in Glaucoma and Ocular hypertension USA and Singapore (Ophthalmic, Liquid) (NCT02622334)
  • 01 Nov 2015 Phase-I clinical trials in Glaucoma and Ocular hypertension in USA (Ophthalmic) (NCT02622334)
  • 16 Oct 2012 Discontinued - Phase-I for Non-alcoholic fatty liver disease in Austria (PO)
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