AMG 557

Drug Profile

AMG 557

Alternative Names: AMG 557/MEDI5872; AMG-557; Anti-B7RP1 MAb; MEDI-5872

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Amgen
  • Developer Amgen; MedImmune
  • Class Monoclonal antibodies
  • Mechanism of Action B7-related protein 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Sjogren's syndrome
  • Phase I Systemic lupus erythematosus
  • Discontinued Cutaneous lupus erythematosus; Psoriasis

Most Recent Events

  • 20 Apr 2016 Amgen completes its phase I trial for Systemic lupus erythematosus in USA, United Kingdom, Denmark, Germany, France, Malaysia, Taiwan and Australia (NCT01683695)
  • 24 Sep 2015 Phase-II clinical trials in Sjogren's syndrome in France (SC)
  • 01 Jun 2015 Phase-II clinical trials in Sjogren's syndrome in USA (SC) (NCT02334306)
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