Drug Profile


Alternative Names: Debio-0824; ShK-186

Latest Information Update: 16 Jul 2016

Price : $50

At a glance

  • Originator Airmid; University of California at Irvine
  • Developer Kineta; KPI Therapeutics; Seattle Childrens Research Institute; University of California at Irvine; University of Groningen
  • Class Amides; Peptides; Proteins
  • Mechanism of Action Kv1.3 potassium channel inhibitors; T lymphocyte modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Plaque psoriasis; Psoriatic arthritis
  • Preclinical Lupus nephritis; Vasculitis
  • Research Inflammatory bowel diseases; Multiple sclerosis
  • No development reported Autoimmune disorders; Obesity

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for phase-I development in Autoimmune-disorders(In volunteers) in Netherlands (SC, Injection)
  • 16 Jul 2016 No recent reports of development identified for preclinical development in Obesity in USA (SC, Injection)
  • 09 Jun 2015 Early research in Inflammatory bowel disease and Multiple sclerosis in USA (Parenteral)
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