AMG 110

Drug Profile

AMG 110

Alternative Names: AMG-110; Anti-CD3 anti-EpCAM bispecific antibody - Amgen; MT110; MT110 monoclonal antibody; Solitumomab

Latest Information Update: 24 Apr 2016

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At a glance

  • Originator Micromet Inc
  • Developer Amgen
  • Class Antineoplastics; Bispecific antibodies
  • Mechanism of Action CD3 antigen inhibitors; Epithelial cell adhesion molecule inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 01 Jan 2015 Amgen completes a phase I trial of AMG 110 in Solid tumours in Germany (NCT00635596)
  • 07 Mar 2012 Micromet Inc has been acquired by Amgen
  • 08 Jun 2010 Interim efficacy & adverse events data from a phase I trial of IV MT 110 in Solid tumours (lung, gastrointestinal) presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO-2010)
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