Drug Profile


Alternative Names: CKD-943; CR 845; FE 202845; MR13A9

Latest Information Update: 02 May 2017

Price : $50

At a glance

  • Originator Ferring Pharmaceuticals
  • Developer Cara Therapeutics; Chong Kun Dang; Maruishi Pharmaceutical
  • Class Opioid analgesics; Peptides
  • Mechanism of Action Opioid kappa receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Postoperative pain
  • Phase II/III Pruritus
  • Phase II Pain

Most Recent Events

  • 24 Apr 2017 Safety data from a phase I trial in Healthy volunteers released by Cara Therapeutics
  • 28 Mar 2017 Top-line safety and efficacy data from a phase II/III trial in Pruritus released by Cara Therapeutics
  • 15 Mar 2017 Maruishi Pharmaceutical and Kissei Pharmaceutical collaborate on difelikefalin in Japan
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