Research programme: metal-protein-attenuating compounds - Prana Biotechnology

Drug Profile

Research programme: metal-protein-attenuating compounds - Prana Biotechnology

Alternative Names: MPAC - Prana Biotechnologies; PBT 519; PBT-434; PBT3 series - Prana Biotechnologies; PBT4 series - Prana Biotechnologies

Latest Information Update: 08 Mar 2016

Price : $50

At a glance

  • Originator Prana Biotechnology
  • Class Quinazolinones
  • Mechanism of Action Alpha-synuclein inhibitors; Iron chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Age-related macular degeneration; Alzheimer's disease; Brain cancer; Parkinson's disease; Parkinsonian disorders
  • Research Neurodegenerative disorders

Most Recent Events

  • 26 Feb 2016 Prana Biotechnology plans a phase I trial for Parkinsonian disorders
  • 26 Feb 2016 Prana Biotechnology announces intention to submit IND for PBT 434
  • 29 Sep 2015 Early research in Neurodegenerative disorders in Australia (unspecified route) before September 2015
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