Research programme: esterase-sensitive motif targeted therapeutics - Macrophage Pharma

Drug Profile

Research programme: esterase-sensitive motif targeted therapeutics - Macrophage Pharma

Alternative Names: CHR 6155; MPL 5821

Latest Information Update: 20 Jan 2017

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At a glance

  • Originator Chroma Therapeutics
  • Developer Chroma Therapeutics; GlaxoSmithKline
  • Class Small molecules
  • Mechanism of Action DNA inhibitors; Histone deacetylase inhibitors; HSP90 heat-shock protein inhibitors; Macrophage colony stimulating factor inhibitors; P38 mitogen-activated protein kinase inhibitors; Polo-like kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer
  • No development reported Inflammation

Most Recent Events

  • 11 May 2017 Macrophage Pharma plans a clinical trial in cancer
  • 20 Jan 2017 No development reported - Preclinical for Inflammation in United Kingdom (PO)
  • 09 Jan 2017 Esterase sensitive motif targeted therapeutics are still under preclinical development in United Kingdom
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