Thioureidobutyronitrile

Drug Profile

Thioureidobutyronitrile

Alternative Names: Kevetrin

Latest Information Update: 29 Dec 2016

Price : $50

At a glance

  • Originator Cellceutix
  • Developer Cellceutix; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Nitriles; Small molecules
  • Mechanism of Action Alkylating agents; Apoptosis stimulants; Caspase 3 stimulants; Poly(ADP-ribose) polymerase modulators; Retinoblastoma protein modulators; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Retinoblastoma; Ovarian cancer
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Ovarian cancer

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Breast cancer; Chronic myeloid leukaemia; Colorectal cancer; Glioblastoma; Head and neck cancer; Lung cancer; Lymphoma; Multiple myeloma; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cancer; Retinoblastoma

Most Recent Events

  • 15 Dec 2016 Preclinical trials in Ovarian cancer in USA (PO)
  • 15 Dec 2016 Cellceutix plans a phase I trial in Ovarian cancer (In volunteers) (PO)
  • 03 Aug 2016 Early research in Cancer in USA (PO)
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