Drug Profile


Alternative Names: CALAA-01

Latest Information Update: 31 Aug 2012

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At a glance

  • Originator Calando Pharmaceuticals
  • Class Small interfering RNA
  • Mechanism of Action Ribonucleotide reductase inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 31 Aug 2012 Calando completes enrolment in its phase Ib trial for refractory Solid tumours in the US
  • 09 Aug 2011 Calando completes enrolment in its phase I trial for Solid tumours in the US
  • 08 Jun 2010 Adverse events data from a phase I trial in Solid tumours presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO-2010)
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