Anti-CD3-anti-HER2/neu-activated T cells - TransTarget

Drug Profile

Anti-CD3-anti-HER2/neu-activated T cells - TransTarget

Alternative Names: Anti-CD3 activated T cells targeted with anti-CD3-anti-HER2 bispecific antibody; ATC targeted with HER2Bi; HER2Bi-armed ATC

Latest Information Update: 05 Aug 2015

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At a glance

  • Originator TransTarget
  • Developer Barbara Ann Karmanos Cancer Institute; National Cancer Institute (USA)
  • Class Bispecific antibodies; Immunotherapies; Monoclonal antibodies; T lymphocyte cell therapies
  • Mechanism of Action Apoptosis stimulants; CD3 antigen inhibitors; ERBB 2 receptor antagonists; Immunostimulants; Macrophage stimulants; Natural killer cell stimulants; T lymphocyte replacements; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Breast cancer

Most Recent Events

  • 18 Dec 2009 Phase-II clinical trials in Breast cancer in USA (IV)
  • 03 Jun 2008 Phase-I clinical trials in Breast cancer in USA (IV)
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