Drug Profile


Alternative Names: AKIi-5; DGFi; I-5NP; QPI-1002; QPI002

Latest Information Update: 07 Aug 2017

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At a glance

  • Originator Quark Pharmaceuticals
  • Class Small interfering RNA
  • Mechanism of Action RNA interference; Tumour suppressor protein p53 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Delayed graft function
  • New Molecular Entity No

Highest Development Phases

  • Phase III Delayed graft function
  • Phase II Acute kidney injury

Most Recent Events

  • 28 Jul 2017 Quark Pharmaceuticals completes a phase II trial in Acute kidney injury (In the elderly, In adults, Prevention) in USA, Canada and Germany (IV) (NCT02610283)
  • 28 Jul 2017 Adverse events data from a phase II trial in Acute kidney injury released by Quark Pharmaceuticals ,
  • 01 Dec 2015 Phase-II clinical trials in Acute kidney injury (Prevention) in USA (IV)
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