Drug Profile


Alternative Names: POL-6326

Latest Information Update: 09 Jul 2017

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At a glance

  • Originator Polyphor
  • Class Antineoplastics; Cyclic peptides; Epitopes; Peptidomimetics
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Asthma; Cancer; Coronary artery restenosis; Inflammation; Stem cell mobilisation; Wounds

Highest Development Phases

  • Phase II Myocardial infarction; Stem cell mobilisation
  • Phase I Breast cancer; Solid tumours; Wounds
  • No development reported Coronary artery restenosis; Inflammation

Most Recent Events

  • 02 Jun 2017 Efficacy and adverse events data from a phase I trial in Breast cancer (Combination therapy) presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 15 Dec 2016 Biomarkers information updated
  • 09 Jun 2016 Polyphor completes the phase II CATCH-AMI trial in Myocardial infarction in Austria, Germany, Hungary, Poland, Norway, Croatia and United Kingdom (NCT01905475; EudraCT 2012-003229-91)
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