Drug Profile


Alternative Names: E-7050

Latest Information Update: 06 Sep 2017

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At a glance

  • Originator Eisai Co Ltd
  • Class Amides; Antineoplastics; Cyclopropanes; Fluorobenzenes; Piperazines; Piperidines; Pyridines; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Proto oncogene protein c met inhibitors; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gastric cancer; Glioblastoma; Head and neck cancer; Hepatocellular carcinoma; Malignant melanoma; Solid tumours

Most Recent Events

  • 15 Nov 2013 Eisai completes enrolment in its phase Ib/II trial for Head and neck cancer (second-line combination therapy, late-stage disease) in USA, United Kingdom, South Korea & Ukraine (NCT01332266)
  • 14 Nov 2013 Phase-I/II clinical trials in Hepatocellular carcinoma (first-line combination therapy, late-stage disease) in Italy & Ukraine (PO)
  • 01 Jul 2013 Eisai completes a phase I trial in Solid tumours in Japan (NCT01428141)
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