Research programme: RNA interference-based cancer therapeutics - Marina Biotech

Drug Profile

Research programme: RNA interference-based cancer therapeutics - Marina Biotech

Alternative Names: Debio 1141; M 400; MDR-09513; MDR-09521; MRNA-046

Latest Information Update: 22 May 2015

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At a glance

  • Originator MDRNA
  • Developer AstraZeneca China; Debiopharm Group; Marina Biotech
  • Class Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Bladder cancer; Hepatocellular carcinoma; Malignant ascites
  • No development reported Urogenital cancer

Most Recent Events

  • 23 Apr 2015 Marina Biotech receives patent allowance for DILA2 technology in Japan, Israel and Europe
  • 25 Feb 2015 Marina Biotech has patent protection for DiLA2 technology in USA, Europe, Japan, China and Australia
  • 27 Aug 2013 Preclinical development is ongoing for bladder cancer and hepatocellular carcinoma in USA
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