Asfotase alfa

Drug Profile

Asfotase alfa

Alternative Names: ALXN1215; Asfotase alpha; ENB-0040; Strensiq

Latest Information Update: 20 Jul 2017

Price : $50

At a glance

  • Originator Enobia Pharma
  • Developer Alexion Pharmaceuticals
  • Class Recombinant fusion proteins
  • Mechanism of Action Alkaline phosphatase stimulants; Esterase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypophosphatasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypophosphatasia
  • Preclinical Neurofibromatoses

Most Recent Events

  • 05 Jul 2017 NICE recommends asfotase alfa for the treatment of paediatric-onset hypophosphatasia
  • 15 May 2017 Adverse events data from a phase II trial in Hypophosphatasia released by Alexion Pharmaceuticals
  • 16 Feb 2017 Alexion Pharmaceuticals has patent protection for Asfotase alfa in Europe
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