Rivipansel

Drug Profile

Rivipansel

Alternative Names: GM-1070; GMI-1070; PF-06460031; PF-6460031

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator GlycoMimetics
  • Developer GlycoMimetics; Pfizer
  • Class Anti-inflammatories; Antianaemics; Antineoplastics; Glycolipids; Naphthalenesulfonates; Pyrimidines; Small molecules
  • Mechanism of Action E-selectin inhibitors; L-selectin inhibitors; P selectin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Sickle cell anaemia
  • Preclinical Haematological malignancies

Most Recent Events

  • 23 Mar 2017 Pfizer completes a phase I pharmacokinetics trial in Healthy volunteers and subjects with hepatic impairment in USA (NCT02871570)
  • 16 Mar 2017 Pfizer completes a phase I trial for Health volunteers in USA (NCT02998099)
  • 26 Jan 2017 Pfizer initiates enrolment in a phase I trial for Health volunteers in USA (NCT02998099)
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