Elobixibat - Albireo AB

Drug Profile

Elobixibat - Albireo AB

Alternative Names: A 3309; AJG 533

Latest Information Update: 03 Jul 2017

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At a glance

  • Originator AstraZeneca
  • Developer Albireo Pharma; EA Pharma
  • Class 2 ring heterocyclic compounds; Amides; Carboxylic acids; Laxatives; Small molecules; Sulfides; Sulfones; Thiazepines
  • Mechanism of Action Sodium-bile acid cotransporter-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Constipation
  • Phase II Irritable bowel syndrome
  • Discontinued Dyslipidaemias

Most Recent Events

  • 14 Nov 2017 Albireo expects a decision from the Japanese Pharmaceuticals and Medical Devices Agency on the approval of elobixibat for Constipation in Japan in the first half of 2018
  • 06 May 2017 Efficacy and adverse event data from a phase-IIb trial in Constipation presented at Digestive Disease Week 2017 (DDW-2017)
  • 31 Mar 2017 Ajinomoto completes a phase III trial in Constipation in Japan (PO) (JapicCTI153061)
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