Research programme: PCSK9 mRNA inhibitors - Roche

Drug Profile

Research programme: PCSK9 mRNA inhibitors - Roche

Alternative Names: LNA PCSK-9; PCSK9 inhibitor

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Santaris Pharma
  • Developer Roche
  • Class Antisense oligonucleotides
  • Mechanism of Action PCSK9 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Hypercholesterolaemia

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Hypercholesterolaemia in Denmark (Parenteral)
  • 05 Jan 2017 CiVi Biopharma and Roche agree to co-promote and co-develop PCSK9 mRNA inhibitors for Hypercholesterolaemia in Denmark
  • 05 Jan 2017 Roche plans a phase I trial for Hypercholesterolaemia
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