PBI 05204

Drug Profile

PBI 05204

Alternative Names: Oleandrin - Phoenix Biotechnology; PBI-05204

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator University of Texas M. D. Anderson Cancer Center
  • Developer Phoenix Biotechnology
  • Class Antineoplastics; Cardenolides
  • Mechanism of Action Apoptosis stimulants; Fibroblast growth factor inhibitors; NF-kappa B inhibitors; Proto oncogene protein c-akt inhibitors; Transcription factor AP-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Pancreatic cancer
  • No development reported Stroke

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Stroke in USA (PO, Capsule)
  • 01 Apr 2015 Phase-II clinical trials in Pancreatic cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT02329717)
  • 06 Jan 2015 Phoenix Biotechnology plans a phase II trial for Pancreatic cancer (Late-stage disease, Metastatic disease) in USA (NCT02329717)
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