Sodium nitrite inhalation - Savara Pharmaceuticals

Drug Profile

Sodium nitrite inhalation - Savara Pharmaceuticals

Alternative Names: AIR-001; Aironite

Latest Information Update: 15 Nov 2017

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At a glance

  • Originator National Heart, Lung and Blood Institute
  • Developer Aires Pharmaceuticals; Mayo Clinic; Savara Pharmaceuticals; University of Pittsburgh
  • Class Antidotes; Antihypertensives; Nitrites; Small molecules; Sodium compounds; Vasodilators
  • Mechanism of Action Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity No

Highest Development Phases

  • Phase II Heart failure; Pulmonary hypertension
  • Phase I/II Pseudomonal infections
  • Discontinued Pulmonary arterial hypertension

Most Recent Events

  • 08 Nov 2017 Savara Pharmaceuticals completes enrolment in the phase III IMPALA trial for Pulmonary alveolar proteinosis in USA
  • 27 Apr 2017 Mast Therapeutics has merged with Savara Pharmaceuticals and will operate under the name Savara Pharmaceuticals
  • 06 Mar 2017 Aires Pharmaceuticals and University of Pittsburgh enter into an agreement for the phase I/II trial in Pseudomonal infections in Cystic fibrosis patients
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