Tavokinogene telsaplasmid

Drug Profile

Tavokinogene telsaplasmid

Alternative Names: DNA IL-12; IL-12 gene therapy; ImmunoPulse; ImmunoPulse®IL-12; Interleukin-12 gene therapy - OncoSec Medical; OMS ElectroImmunotherapy™; pIL-12; pIL-12 Electroporation; Plasmid IL-12

Latest Information Update: 10 Jun 2017

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At a glance

  • Originator Inovio Biomedical Corporation
  • Developer Fred Hutchinson Cancer Research Center; Massachusetts General Hospital; OncoSec Medical; University of California at San Francisco; University of Washington
  • Class Antineoplastics; Cytokine genes; Gene therapies; Immunotherapies; Interleukins
  • Mechanism of Action Gene transference; Immunomodulators; Immunostimulants; Interleukin-12 expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Breast cancer; Cutaneous T cell lymphoma; Head and neck cancer; Malignant melanoma; Merkel cell carcinoma
  • Preclinical Solid tumours

Most Recent Events

  • 08 Jun 2017 Tavokinogene telsaplasmid receives Orphan Drug status for Malignant melanoma in USA
  • 10 May 2017 OncoSec Medical and Merck plan the phase II PISCES trial for Malignant melanoma (Late-stage disease, Second-line therapy or greater, Combination therapy, Metastatic disease) in June 2017
  • 01 Mar 2017 Interleukin-12 gene therapy - OncoSec Medical receives Fast Track designation for Malignant melanoma (Late-stage disease, Metastatic disease, Second-line therapy or greater) (Intratumoural, Injection) in USA
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