Drug Profile


Alternative Names: VCH-222; VX-222

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator ViroChem Pharma
  • Developer Vertex Pharmaceuticals
  • Class Antivirals; Small molecules
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis C

Most Recent Events

  • 26 Jul 2016 Trek Therapeutics acquires lomibuvir from Vertex Pharmaceuticals
  • 15 May 2014 Vertex Pharmaceuticals completes a phase II trial in Hepatitis C (treatment-naive, combination therapy) in USA, Canada, Germany, Poland and United Kingdom (NCT01516918)
  • 01 Feb 2014 Vertex Pharmaceuticals terminates phase II ZENITH trial in Hepatitis C (treatment-naive, in combination with telapravir) in US and New Zealand (NCT01080222)
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