3K3A-APC

Drug Profile

3K3A-APC

Alternative Names: 3K3A-activated protein C; 3K3A-APC non-anticoagulant mutant - ZZ Biotech; Activated protein C analogue with reduced anticoagulant activity -ZZ Biotech; Genetically engineered variant of recombinant human wild-type activated Protein C (APC) - ZZ Biotech; Recombinant variant of human activated protein C (3K3A-APC)

Latest Information Update: 10 Jul 2017

Price : $50

At a glance

  • Originator Socratech; The Scripps Research Institute; University of Southern California
  • Developer The Scripps Research Institute; University of Southern California; University of Sydney; ZZ Biotech
  • Class Antithrombotics; Blood proteins; Enzyme precursors; Recombinant proteins; Serine endopeptidases
  • Mechanism of Action Activated protein C receptor modulators; Factor V inhibitors; Factor VIII inhibitors; PAR 1 receptor modulators; PAR-3 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Stroke

Highest Development Phases

  • Phase II Stroke
  • Preclinical Amyotrophic lateral sclerosis; Diabetic foot ulcer; Neurological disorders; Septic shock

Most Recent Events

  • 10 Jul 2017 Preclinical trials in Diabetic foot ulcer in USA (IV) before July 2017 (ZZ Biotech pipeline, July 2017)
  • 10 Jul 2017 ZZ Biotech announces intention to submit IND to US FDA for Diabetic foot ulcer in 2017 (ZZ Biotech pipeline, July 2017)
  • 10 Jul 2017 ZZ Biotech plans a phase II trial for Diabetic foot ulcer in USA in 2017 (ZZ Biotech pipeline, July 2017)
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