Tanzisertib

Drug Profile

Tanzisertib

Alternative Names: CC-930; JNK CC-930; JNK-930

Latest Information Update: 30 Jul 2015

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At a glance

  • Originator Celgene Corporation
  • Class Antifibrotics; Small molecules
  • Mechanism of Action JNK mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Discoid lupus erythematosus; Idiopathic pulmonary fibrosis

Most Recent Events

  • 16 Jul 2012 Celgene Corporation terminates a phase II trial in Discoid lupus erythematosus in USA (NCT01466725)
  • 23 Feb 2012 Celgene initiates enrolment in a phase II trial for Discoid lupus erythematosus in the USA (NCT01466725)
  • 08 Nov 2011 The Committee for Orphan Medicinal Products (COMP) recommends orphan drug designation for tanzisertib in European Union for Idiopathic pulmonary fibrosis
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