Drug Profile


Alternative Names: ALUNBRIG; AP-26113

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator ARIAD Pharmaceuticals
  • Class Antineoplastics; Diamines; Piperazines; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; Epidermal growth factor receptor antagonists; ROS1-protein-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Non-small cell lung cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Non-small cell lung cancer
  • No development reported Lymphoma; Neuroblastoma

Most Recent Events

  • 02 Jun 2017 Updated efficacy and adverse events data from the phase II ALTA trial in Non-small-cell lung cancer presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 31 May 2017 ARIAD Pharmaceuticals completes an expanded-access programme for Non-small cell lung cancer (Metastatic disease, Late-stage disease, Second-line therapy or greater) in USA (PO) (NCT02784158)
  • 11 May 2017 Brigatinib licensed to Biologics Inc. in USA
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