Drug Profile


Alternative Names: [14C]-plazomicin; ACHN-490; Plazomicin sulfate

Latest Information Update: 18 Jul 2017

Price : $50

At a glance

  • Originator Isis Pharmaceuticals
  • Developer Achaogen
  • Class Aminoglycosides; Antibacterials; Small molecules
  • Mechanism of Action Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Bacteraemia; Nosocomial pneumonia; Pyelonephritis; Urinary tract infections
  • Preclinical Gram-negative infections; Respiratory tract infections; Tularaemia; Yersinia infections

Most Recent Events

  • 18 Jul 2017 Achaogen completes a phase I trial in Healthy volunteers in USA (NCT03177278)
  • 06 Jun 2017 Achaogen initiates enrolment in a phase I trial in Healthy volunteers in USA (NCT03177278)
  • 05 Jun 2017 Updated efficacy data from the phase III EPIC and CARE trials in Urinary tract infections and Bacteraemia presented at the American Society for Microbiology Microbe Annual Meeting (ASM-2017)
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