Drug Profile


Alternative Names: AB-1010; Masican; Masipro; Masitinib mesilate; Masitinib mesylate; Masiviera

Latest Information Update: 03 Aug 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator AB Science
  • Class Antiasthmatics; Antineoplastics; Antirheumatics; Benzamides; Nootropics; Piperazines; Pyridines; Small molecules; Thiazoles
  • Mechanism of Action Colony stimulating factor inhibitors; Focal adhesion protein-tyrosine kinase inhibitors; Platelet derived growth factor alpha receptor antagonists; Platelet-derived growth factor receptor antagonists; Protein tyrosine kinase inhibitors; Proto oncogene protein c-kit inhibitors; Type 3 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mastocytosis; Amyotrophic lateral sclerosis; Gastric cancer; Gastrointestinal stromal tumours; Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Amyotrophic lateral sclerosis; Mastocytosis
  • Phase III Alzheimer's disease; Asthma; Colorectal cancer; Gastrointestinal stromal tumours; Malignant melanoma; Multiple myeloma; Pancreatic cancer; Peripheral T-cell lymphoma; Prostate cancer
  • Phase II/III Crohn's disease; Multiple sclerosis; Ovarian cancer; Progressive supranuclear palsy
  • Phase II Breast cancer; Chronic obstructive pulmonary disease; Head and neck cancer; Mood disorders; Non-small cell lung cancer; Parkinson's disease
  • Phase I/II Gastric cancer; Glioblastoma; Hepatocellular carcinoma; Oesophageal cancer
  • Preclinical Stroke
  • No development reported Psoriasis
  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 12 Jul 2017 AB Science has patents pending for masitinib in Pancreatic cancer in USA
  • 12 Jul 2017 The patent offices of Europe, Singapore and South Africa each issue a Notice of Allowance for a patent relating to masitinib in Pancreatic cancer
  • 12 Jul 2017 Updated efficacy data from a phase III trial in Pancreatic cancer released by AB Science
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