CC 223

Drug Profile

CC 223

Alternative Names: CC-223

Latest Information Update: 22 May 2017

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At a glance

  • Originator Celgene Corporation
  • Class Antineoplastics
  • Mechanism of Action MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Multiple myeloma; Non-Hodgkin's lymphoma; Solid tumours
  • Phase I Diffuse large B cell lymphoma; Non-small cell lung cancer
  • Preclinical Prostate cancer

Most Recent Events

  • 09 Dec 2016 Celgene completes a phase I/II trial in Solid tumours, Non-Hodgkin's lymphoma and Multiple myeloma (Late-stage disease, Second-line therapy or greater) in USA, France, Spain and United Kingdom (NCT01177397)
  • 03 Dec 2016 Efficacy and adverse event data from a phase Ib trial in Diffuse large B-cell lymphoma presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-2016)
  • 18 Sep 2015 CC 223 is still in phase I/II trials for Multiple myeloma, Non-Hodgkin's lymphoma and Solid tumours in the USA
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